GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9473555 | 1 | rs9463479 | chr6:49393275 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463480 | chr6:49400795 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.39 | 2.98E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463480 | chr6:49400795 | MUT | chr6:49398994-49431031:- | 0.27 | 4.23 | 5.4E-5 | Folate pathway vitamin levels |
| THYM | cis | rs2275426 | 1 | rs946529 | chr1:46485548 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6.02 | 3.21E-8 | Body mass index |
| THYM | cis | rs6911965 | 1 | rs9467176 | chr6:24464907 | GPLD1 | chr6:24428405-24489850:- | -0.45 | -4.67 | 9.97E-6 | Hematological and biochemical traits |
| THYM | cis | rs6911965 | 1 | rs9467182 | chr6:24468654 | GPLD1 | chr6:24428405-24489850:- | 0.45 | 4.67 | 9.97E-6 | Hematological and biochemical traits |
| THYM | cis | rs6911965 | 1 | rs9467190 | chr6:24474771 | GPLD1 | chr6:24428405-24489850:- | 0.44 | 4.56 | 1.5E-5 | Hematological and biochemical traits |
| THYM | cis | rs9473555 | 1 | rs9473549 | chr6:49380020 | CENPQ | chr6:49431096-49460820:+ | -0.23 | -4.18 | 6.53E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9473549 | chr6:49380020 | MUT | chr6:49398994-49431031:- | 0.28 | 4.37 | 3.17E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9369898 | 1 | rs9473550 | chr6:49385182 | CENPQ | chr6:49431096-49460820:+ | -0.26 | -4.77 | 6.65E-6 | Homocysteine levels |
| THYM | cis | rs9473555 | 1 | rs9473552 | chr6:49387154 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9473552 | chr6:49387154 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9473553 | chr6:49395977 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9473553 | chr6:49395977 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9473555 | chr6:49409487 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |